TRI facility · TRI 2024 reporting year

Ionis Pharmaceuticals INC.

Total reported releases 5 lb more than doubled year over year (+85%). Total releases concentrations have more than halved since 2010.

2282 FARADAY AVENUE, Carlsbad, California · 325411 · Chemicals

TOTAL RELEASES · 20102024
Bar chart of annual values from 2010 to 2024, in lb. Most recent year (2024): 5.12'10'12'14'16'18'20'22'245
Anomaly engine

Notable Signals

No notable signals at this facility for the current reporting year. See chemicals and equity context below for the full picture.

Chemicals reported · most recent year

What This Facility Releases

RESPIRATORYCAS 75-05-8

Acetonitrile

3 lb · +99% YoY

Acetonitrile concentrations have more than halved since 2010.

RESPIRATORYCAS 67-56-1

Methanol

2 lb · +50% YoY

Methanol concentrations are roughly unchanged from 2010.

RESPIRATORYCAS 108-88-3

Toluene

1 lb · +133% YoY

Toluene volumes here are too small to anchor a multi-year trend; YoY movement is still shown above.

CARCINOGENCAS 110-86-1

Pyridine

0 lb · YoY

Pyridine volumes here are too small to anchor a multi-year trend; YoY movement is still shown above.

Equity context · ACS 2018-2022 block-group demographics

Who Lives Next To This Facility

Within 3 miles of this facility (41 Census block groups, population-weighted demographics): a population of 70,872. Why we surface this →

POPULATION SHARE
17.5%

Low-income

POPULATION SHARE
36.9%

People of color

POPULATION SHARE
4.3%

Under age 5

POPULATION SHARE
18.3%

Over age 64

Source: Census ACS 2018-2022 block-group demographics, population-weighted across the 3-mile buffer around this facility (from USEPA-clone/EJAM-open blockgroupstats). Indicator-level percentile and EJ-disparity scores are surfaced on the county page and the state page — they describe wider regional exposure burdens, not effects attributable to a single facility.

Source. EPA Toxics Release Inventory · retrieved 2026-05-07. Reporting year 2024. TRI is a federal public-domain dataset under 17 USC §105.

What this is not. TRI quantifies releases reported by the facility under EPCRA §313 — not ambient air or water concentrations measured at receptors. We do not attribute individual health outcomes to specific facilities; that exceeds what the data can support.