TRI facility · TRI 2024 reporting year

Sigma-Aldrich Manufacturing LLC

Total reported releases 50k lb more than doubled year over year (+79%). Total releases concentrations have more than doubled since 2010.

3300 S SECOND ST, Saint Louis, Missouri · 325199 · Chemicals · operated by Emd Holding CORP

TOTAL RELEASES · 20102024
Bar chart of annual values from 2010 to 2024, in lb. Most recent year (2024): 50k.159k'10'12'14'16'18'20'22'2450k
Anomaly engine

Notable Signals

YEAR-OVER-YEAR SURGE · RELEASE SHIFT

Ethylene glycol

Ethylene glycol releases at Sigma-Aldrich Manufacturing LLC rose from 2k lb to 27k lb (11.7×) between 2023 and 2024.

Chemicals reported · most recent year

What This Facility Releases

RESPIRATORYCAS 107-21-1

Ethylene glycol

27k lb · +1066% YoY

Ethylene glycol concentrations have more than doubled since 2014.

GENERALCAS 7664-41-7

Ammonia

16k lb · +6% YoY

Ammonia concentrations have fallen 16% since 2014.

RESPIRATORYCAS 67-56-1

Methanol

5k lb · -34% YoY

Methanol concentrations are roughly unchanged from 2010.

CARCINOGENCAS 67-66-3

Chloroform

1k lb · -36% YoY

Chloroform concentrations are roughly unchanged from 2010.

CARCINOGENCAS 75-09-2

Dichloromethane

505 lb · -1% YoY

Dichloromethane concentrations are roughly unchanged from 2011.

RESPIRATORYCAS 121-44-8

Triethylamine

96 lb · -64% YoY

Triethylamine concentrations have more than halved since 2010.

Equity context · ACS 2018-2022 block-group demographics

Who Lives Next To This Facility

Within 3 miles of this facility (99 Census block groups, population-weighted demographics): a population of 101,360. Why we surface this →

POPULATION SHARE
39.4%

Low-income

POPULATION SHARE
52.8%

People of color

POPULATION SHARE
5.8%

Under age 5

POPULATION SHARE
10.3%

Over age 64

Source: Census ACS 2018-2022 block-group demographics, population-weighted across the 3-mile buffer around this facility (from USEPA-clone/EJAM-open blockgroupstats). Indicator-level percentile and EJ-disparity scores are surfaced on the county page and the state page — they describe wider regional exposure burdens, not effects attributable to a single facility.

Source. EPA Toxics Release Inventory · retrieved 2026-05-07. Reporting year 2024. TRI is a federal public-domain dataset under 17 USC §105.

What this is not. TRI quantifies releases reported by the facility under EPCRA §313 — not ambient air or water concentrations measured at receptors. We do not attribute individual health outcomes to specific facilities; that exceeds what the data can support.